PROCESS FOR THE PREPARATION OF 3-AMINO-4-HYDROXY-8-METHYL-7-3-0(2-PYRROLYLCARBONYL) NOVIOSYLOXYI COUMARIN AND 3-AMINO-4-HYDOXY-8-METHYL-7-3-0(5-METHYL-2-PYRROLYLCARBONYL) NOVIOSYLOXY COUMARIN, AND SALTS THEREOF

摘要

. A process for the preparation of compounds of the formula III of the accompanying drawings, wherein R1 is hydrogen or methyl, and salts thereof: which process comprises hydrogenating, by methods known per se, such as herein defined a compound of the formula IV of the drawings, wherein R1 is as described above and R3 and R4 each are hydrogen, fluoro, chloro, bromo, nitro, cyano, (lower) alkyl or (lower) alkoxy, in an inert solvent, in the presence of a catalyst, at a temperature of from about-10 0X. to about 50C.