Imidazolyl alkyl-phenyl - (thio) ethers - active against dermatophytes, yeasts, protozoa bacterial and fungal diseases

摘要

Imidazole derivs. (I) their salts and medicaments contg. (I): (where X is a direct bond or -(CH2)n-CH-R1; n is 0, 1 or 2; R1 is H, 1-6C alkyl, phenyl opt. substd. by halogen, 1-6C alkyl or -alkoxy or NO2; R2 and R3 are H, 1-10C alkyl, 1-6C alkoxy or alkylthio, halogen or NO2 or R2+R3 is C4H4; R4 is 3-6C alkynyl, phenyl opt. substd. by halogen, NO2, CF3, 3-6C alkynyl, 1-6C alkyl or alkoxy, phenyl (1-4C alkyl) opt. substd. in the ring by halogen, NO2, CF3, 1-6C alkyl or alkoxy; R4 is also 1-6C alkyl when n is O, and X is O, S or NH) are active against dermatophytes, yeasts, protozoa, Gram-positive and negative bacteria and diseases caused by fungi.