Dibenzo (b,f) (1,4)-oxazepines - neuroleptics, antiemetics - esp 2-trifluoromethylsulphonyl-11-(4-beta-acyloxy-ethyl-1-piperazin

摘要

Novel title cpds have formula: (where Z = ethylene and R1 = isopropyl, butyl, pentyl or isopentyl) including their acid addition salts. In the parent patent, A = 1-3C alkylene and R1 = opt. unsatd. 3-18C aliphatic gp. A specific cpd. is 2-trifluoromethylsulphonyl-11- (4-beta-isobutyryloxy-ethyl-1-piperazinyl)-dibenzo [b,f] [1,4]-oxazepine.