improved composition for the demonstration of the fibrin monomers and of the products of degradation of fibrin, its process of preparation and its application in the diagnosis of coagulation intravascular spread

摘要

A method for detecting fibrin and fibrin degradation products in blood plasma which involves mixing the blood sample with a composition containing protamine sulfate and finely divided colored particles and visually observing the resultant colored fibrin strands and colored fibrin gels in a positive test. The composition is prepared by gradually adding a saline solution of the colored particles to a saline solution of the protamine sulfate and the pH is adjusted to 6.5 +/- 0.05.