Chlorpromazine assay

摘要

A sensitive radioimmunoassay for chlorpromazine is described. To prepare the chlorpromazine selective antiserum, an antigen is made comprising chlorpromazine covalently bonded to an immunogenic carrier material through a diazo containing linking group and the antigen is injected into a suitable host mammal to elicit the desired antiserum. A preferred linking group is diazophenylcarbonyl while bovine serum albumin is a preferred immunogenic carrier material.