ISOLATION OF A PLACENTA-SPECIFIC GLYCOPROTEIN.

摘要

In order to concentrate the placenta-specific protein PP5, a PP5-containing protein solution is brought into contact, at a pH of between 4 and 9, with an antibody against PP5 which is bound to an insoluble support. The support with the PP5 bound to it is separated off from the liquid phase. In order to release the PP5, this support is treated with an aqueous medium of a pH of from 2 to 4, or with a solution of a substance which dissociates protein bonds at a pH of from 4 to 9. The PP5 which is obtained can be used in a diagnostic agent for detecting PP5 and antibodies directed against PP5.