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process for the production of new n - (o - acylaminophenyl) - n '- acylisothioharnstoffathern
process for the production of new n - (o - acylaminophenyl) - n '- acylisothioharnstoffathern
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机译:新的正-(邻-酰基氨基苯基)-n'-酰基异硫代harnstoffathern的生产方法
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摘要
N-[2-(Substituted amido)phenyl]-N'-carbonyl-S-substituted isothioureas bearing an optionally substituted phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl group in the 4- or 5-position of the 2-(substituted amido)-phenyl group are anthelmintic agents. The compounds, of which N-(2-acetamido-4-phenoxyphenyl)-N'-carbomethoxy-S-methylthiourea is a typical example, are prepared through the reaction of S-substituted N-(mercaptohalomethylene)carbamic acid ester and an apropriately substituted 2-aminoanilide, or through alkylation of the corresponding S-unsubstituted thiourea.
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