Procedure for obtaining agents of contrast to x-rays. (Machine-translation by Google Translate, not legally binding)

摘要

"PROCEDURE FOR OBTAINING AGENTS OF CONTRASTS TO X-RAYS" which is characterized by the preparation of 3, N-methyl acetamido-5-amino-2,4,6-triiodobenxoic acid, by reacting 3-acetylamino, 5-aminobenzoic acid (I) ) with Cl2IK, obtaining the corresponding triiodinated derivative (II) ** (See formula) ** which is treated with methyl p-toluene sulfonate is transformed into the E-methyl derivative (III) ** (See formula) ** which is acetylated in acidic medium to lead to 3, N-methyl acetamido acid, acetamide 2,4,6 triiodo benzoic acid (Metrizoic acid) (IV). ** (See formula) ** (Machine-translation by Google Translate, not legally binding)