Procedure for the preparation of 6-aminopenicilanico or 7-aminodexacetoxicefalosporanico ácidos derivados. (Machine-translation by Google Translate, not legally binding)

摘要

Procedure for the preparation of 6-aminopenicillanic or 7-aminodexacetoxycephalosporanic acids, of the general formula **(See formula)** in which R represents the phenyl group, optionally substituted by a hydroxide group or by 1,4-cyclohexadieniol radical and Y represents the rest of 7-aminodexacetoxycephalosporanic acid characterized by the fact that 6-aminopenicillanic acid or 7-aminodexacetoxicophalosporanic acid reacts in an appropriate solvent with N, N'-bis-trimethylsilylurea at the boiling temperature of the solvent then achieves the reaction of the mixture with the halo-acid salt of the acid halide selected from the group consisting of 2-amino-2-2 (1, 4-cyclohexadienyl) acetic acid, all of them in their D (-) or L (+) forms or a combination of both, and after separating the trimethisilyl group, the desired compound I is obtained. (Machine-translation by Google Translate, not legally binding)