Random copolymer contg. quat. ammonium ester of unsatd. acid - with high water adsorption and bacteriostatic action, esp. for medical use

摘要

A random copolymer is prepd. by copolymerisation of (A) (1) 10-90 (10-80) wt.% of an ester of an alpha, beta-olefinically unsatd. carboxylic acid and a mono- or poly-alcohol with a terminal quat. ammonium group and (2) 90-10% of =1 alpha, beta-olefinically unsatd. comonomer which can be dispersed in an aq. medium, in presence of (B) =0.02% of a difunctional monomer, which is an ester or amide of an alpha, betha-olefinically unsatd. carboxylic acid and which is dispersible or sol. in an aq. medium, as cross-linking agent. The comonomer (2) consists of (a) =10% of an acid monomer, or (b) =20% of an amide monomer, or (c) =10% of a mixt. of acid and amide monomers contg. =5% of an acid monomer. The copolymers can be used as lubricant coatings on medical appts., e.g. rectoscopes, rectal thermometers, and surgical gloves, to form articles such as contact lenses, or to produce transparent self-supporting films, for use as e.g. wound dressings. As a dry powder, the copolymer can be used as a thickener in aq. coatings compsns., or be used in paper prods., e.g. as handkerchiefs or disposable napkins for babies. The copolymers are hydrophilic, with high water absorption capacity (10-125x the wt. of the copolymer) and are bacteriostatic. Copolymerisation gives a hydrocolloidal dispersion with viscosity 40-10000 cS at 25 degrees C, which is stable for 1-24 months at room temp.