5,11 - diaza tetra cyclo bracket on 6.2.2.0 high 2,7 .0 high 4,9 bracket to dodecanes

摘要

A new heterocycle, 5,11-diazatetracyclo[6.2.2.02,7.04.9]dodecane, is prepared by heating an endo-diazatricyclo[6.2.2.02,7]dodec-11-ene substituted in the 7 and 11 positions with electron withdrawing groups. 2,9-Bis-phenylacetyl derivatives of the new heterocycle and closely related derivatives are potent analgesic agents.