Steroid inters from 3-beta-acyloxy pregnanones - by fungal fermentation with calonectra decora to give 12-beta-15-alpha-dihydroxy-3-acyloxy pregnanones(20)

摘要

Cpds of the formula (I): (where R=2-8C acyl, esp. CH3CO) as inters. which are esp. suitable for the synthesis of digitalisglycosides by known methods. (I) is prepd by fermentation under submerged aerobic conditions. Good yields are obtd. without hydrolysing the 3-acyl gp.