Genes which encode BMP-2 and BMP-4 proteins, vectors which contain such genes, cells which are transformed with such vectors, BMP-2 and BMP-4 proteins, a process for preparing them, and pharmaceutical preparations thereof, and the use thereof

摘要

An artificial kidney in which blood is pumped to and from a first compartment of a dialysis apparatus and dialysis liquid is pumped to and from a second compartment thereof. The hydrodynamic resistance within these compartments is arranged so that one simultaneously maintains a first zone of the apparatus in which the pressure of the blood in the first compartment is higher than the pressure of dialysis liquid in the second compartment and a second zone in which the pressure of the blood in the first compartment is lower than the pressure of the dialysis liquid in the second compartment. By this means in the first zone ultrafiltration occurs from the blood to the dialysis liquid and in the second zone ultrafiltration occurs to inject materials back into the bloodstream from the dialysis liquid.