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SPIROTETRAHYDROPYRANS AND SPIROTHIATETRAHYDROPYRANS
SPIROTETRAHYDROPYRANS AND SPIROTHIATETRAHYDROPYRANS
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机译:螺四氢吡喃和螺吡喃四氢吡喃
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1456955 Spiro-(thia)tetrahydropyrans ROUSSEL UCLAF 8 May 1975 [8 May 1974] 19486/75 Heading C2C Novel compounds I in which X is O or S, R is H or C 1-4 alkyl, n is 2 to 4 and RSP1/SP is H or C 1-12 acyl, are prepared by reducing a compound II in which RSP1/SP 1 is H or C 1-8 alkyl, and, if desired, esterifying the resulting compound I in which RSP1/SP is H to obtain a compound I in which RSP1/SP is C 1-12 aryl. Pharmaceutical compositions having antiinflammatory and analgesic activity, for oral, rectal, parenteral or topical administration, comprise a compound I together with a pharmaceutical carrier or excipient.
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