Treatment of meningeal leukemia with diamino dichlorophenyl pyrimidine

摘要

Method and pharmaceutical preparations for treating meningeal leukemia, CNS Iymphoma and neoplasma in the brain which comprises treating an infected mammal such as a human with a dose of an effective treatment amount of a compound of Formula I ##STR1## where R is a straight or branched chain lower alkyl of 1 to 4 carbon atoms, and X is a halogen atom (fluorine, chlorine, bromine or iodine) and pharmaceutically acceptable salts thereof.PPPreferred compounds for treatment of the aforementioned diseases are 2,4-diamino-5-(3',4'- dichlorophenyl)-6-methylpyrimidine and 2,4-diamino-5-(3',4'- dichlorophenyl)-6-ethylpyrimidine.