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A process for the preparation of 1-aryl-N-dialkylaminoalkyl-3,4-dihydro-2 (1H) -isoquinolincarboxamider or their pharmaceutically acceptable acid addition salts or quaternary ammonium salts.
A process for the preparation of 1-aryl-N-dialkylaminoalkyl-3,4-dihydro-2 (1H) -isoquinolincarboxamider or their pharmaceutically acceptable acid addition salts or quaternary ammonium salts.
1-Aryl-N-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecarboxamides and related N-substituted amides having anti-arrhythmic, anti-bacterial, anti-fungal, anti-algal and anthelmintic activity are described herein. The subject compounds can be prepared by reacting the appropriate 3,4-dihydro-2(1H)-isoquinolinecarbonyl chloride with a dialkylaminoalkylamine or similar compound, or by reacting an N-(chloroalkyl)-3,4-dihydro-2(1H)-isoquinolinecarboxamide with the appropriate dialkylamine or similar compound.
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