A compound of the formula (I), and pharmaceutically acceptable salts thereof: IMAGE (I) wherein: R1 is a C1-6 alkoxy group; R2 and R3 are the same or different and are hydrogen, halogen, CF3, hydroxy, C1-6 alkoxy, C2-7 acyl, amino, amino substituted by one or two C1-6 alkyl groups, C2-10 acyl amino, aminosulphone, aminosulphone substituted by one or two C1-6 alkyl groups, C1-6 alkyl sulphone or nitro groups; and A is a C2-4 alkylene group; R5 and R6 are joined so that they form with the -N-A-N- group to which they are attached, a 6, 7 or 8 membered heterocyclic ring; R7 is a C1-6 alkyl group, or an aryl -C1-6 akyl group in which the alkyl moiety is optionally substituted by a C1-6 alkyl or aryl group; have useful pharmacological activity, such as the ability to regulate the gastrointestinal function and to treat emesis.
展开▼
