首页>
外国专利>
still for framstellning of isoindolinderivat with therapeutic effect
still for framstellning of isoindolinderivat with therapeutic effect
展开▼
机译:仍用于对异吲哚美茵的framstelling具有治疗效果
展开▼
页面导航
摘要
著录项
相似文献
摘要
Compounds of the general formula: IMAGE in which A is a benzene ring or a carbocyclic aromatic group consisting of two or three fused benzene rings, the group A being linked to the nitrogen containing ring at two adjacent carbon atoms and the benzene ring or each benzene ring optionally carrying one or more substituents which may be the same or different, and may be alkyl, aryl, halo, hydroxy, acyloxy or alkoxy, or two adjacent positions in a ring may be substituted so as to form a methylene dioxy group (-O-CH2-O-); R1 and R2 which may be the same or different, each represent hydrogen; an alkyl group which contains 1 to 6 carbon atoms and which may be substituted; a hydroxycarbonyl or an alkoxycarbonyl group; and one of R3 and R4 represents hydrogen, an alkyl group which contains 1 to 6 carbon atoms and which may be substituted, or a hydroxy, alkoxy, hydroxycarbonyl or alkoxycarbonyl group and the other of R3 and R4 represents hydrogen, or a non-toxic physiologically acceptable salt or bioprecursor thereof. These compounds are useful in the treatment of patients suffering from depression.
展开▼
机译:通式:的化合物,其中A是苯环或由两个或三个稠合苯环组成的碳环芳族基团,基团A在两个相邻的碳原子上与含氮环相连,并且苯环或每个苯环任选地带有一个或多个可以相同或不同的取代基,并且可以是烷基,芳基,卤素,羟基,酰氧基或烷氧基,或者可以取代环上的两个相邻位置以形成亚甲基二氧基(-O-CH2-O-); R 1和R 2可以相同或不同,分别表示氢。含有1至6个碳原子并且可以被取代的烷基;羟羰基或烷氧羰基; R3和R4之一表示氢,含1至6个碳原子的可被取代的烷基或羟基,烷氧基,羟基羰基或烷氧羰基,而R3和R4中的另一个表示氢或无毒生理上可接受的盐或其生物前体。这些化合物可用于治疗抑郁症患者。
展开▼