A procedure for the preparation of substituted derivatives in proposition 4 of 1.1 dioxide of (2H, 6h) -1,2,6-tiadiazin-3-ona and its salts. (Machine-translation by Google Translate, not legally binding)

摘要

A process for the preparation of derivatives substituted in position 4 of 11 (2H6H) -126-thiadiazin-3-Ona dioxide and its salts of general formula I indicated below *** (See formula I) Wherein R1 represents the radicals nitro, cyano, sulfamoyl, alkoxycarbonyl, formyl, alkyl, carbonyl, fluorine, fluorine, chlorine, bromine, iodine, etc., and Me means indifferently Hpotassium or sodium characterized by a reaction step indicated below. Unique stage: Condensation of sulfamide of formula *** (See formula II) with an acrylic acid derivative of general formula II *** (See formula III) in which R1 maintains the mentioned significance for the compounds of general formula (I) and R2 and R3 represent either alkylaryl or aralkyl groups in the presence of an alcoholate or its mixtures of general formula III *** (See formula IV) (Machine-translation by Google Translate, not legally binding)