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3-Pyridyl amino ergoline derivs - for treatment of galactorrhoea, breast cancer, oedema, hypertension, parkinsons disease etc.

机译:3-吡啶基氨基麦角灵衍生物-用于治疗半乳痛,乳腺癌,水肿,高血压,帕金森病等

摘要

Ergoline derivs. of formula (I) and their salts: (where R = 3-pyridyl, opt. subst. by one or more of the following: halogen, hydroxy, phenoxy, lower alkyl, alkoxy and alkylthio, and -N-R1R2, R1 and R2 = H or lower alkyl) are useful as prophylaxis and for the treatment of physiological lactation, galactorrhea, and breast cancer, treatment of chronic renal nephropathia and inflammation, the regulation of electrolytic and hydric balance, treatment of oedema, hypertension, migraine attacks, pre-menstrual syndrome, and Parkinson's disease.
机译:麦角灵衍生。式(I)的式(I)及其盐:(其中R = 3-吡啶基,优选被以下一种或多种取代:卤素,羟基,苯氧基,低级烷基,烷氧基和烷硫基,以及-N-R1R2,R1和R2 = H或低级烷基)可用于预防和治疗生理性泌乳,溢乳和乳腺癌,治疗慢性肾肾病和炎症,调节电解质和水分平衡,治疗水肿,高血压,偏头痛,月经前综合征和帕金森氏病。

著录项

  • 公开/公告号FR2267781B1

    专利类型

  • 公开/公告日1978-08-04

    原文格式PDF

  • 申请/专利权人 SANDOZ SA;

    申请/专利号FR19750011771

  • 发明设计人

    申请日1975-04-16

  • 分类号A61K31/48;C07D457/12;

  • 国家 FR

  • 入库时间 2022-08-22 21:49:25

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