Ergoline derivs. of formula (I) and their salts: (where R = 3-pyridyl, opt. subst. by one or more of the following: halogen, hydroxy, phenoxy, lower alkyl, alkoxy and alkylthio, and -N-R1R2, R1 and R2 = H or lower alkyl) are useful as prophylaxis and for the treatment of physiological lactation, galactorrhea, and breast cancer, treatment of chronic renal nephropathia and inflammation, the regulation of electrolytic and hydric balance, treatment of oedema, hypertension, migraine attacks, pre-menstrual syndrome, and Parkinson's disease.
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