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Methods for the preparation of controlled gastric residence time medicament formulations
Methods for the preparation of controlled gastric residence time medicament formulations
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机译:受控胃停留时间药物制剂的制备方法
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摘要
Controlled gastric residence time medicament formulations, e.g. , tablets and/or capsules, containing polymeric film coatings are exposed to a volatile amine, e.g., anhydrous ammonia, methyl amine, or ethyl amine, to provide improved medicament formulations, which by virtue of mechanical or surface effects including expansion or swelling of the coating in gastric fluids are capable of prolonged, e.g., up to twelve hours, residence in the gastric area.
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