foerfarande foer framstaellning av terapeutiskt anvaendbara 3 - amino - 5 6 - dihydro - 8 9 - dialkoxiimidazo (5 1 - (a) isokinolinderivat

摘要

The novel aminopyrazoloisoquinoline derivatives of the formula IMAGE in which A denotes an alkoxy group containing 1 to 4 carbon atoms and D denotes hydrogen, acyl, alkyl or aralkyl, have a favourable effect on the activity of the heart. They are prepared by treating compounds of the general formula IMAGE in which A has the above meaning and R denotes an alkyl, aralkyl or aryl group, with a strong alkaline solution. Compounds of the formula I are thus obtained, in which D denotes hydrogen which can be replaced by an acyl group. This hydrogen can also be replaced by an alkyl or aralkyl group by reaction with an aldehyde or ketone and subsequent reduction of the resulting intermediate.