DIFFERENTIAL ASSAY OF CREATINE PHOSPHOKINASE ISOENZYMES

摘要

Abstract of the DisclosureA process for the determination of creatinephosphokinase MB-isoenzyme (CPK-MB) level inserum in which CPK is determined before and afterMB-activation with 1,4-dimercapto-2,3-dihydroxybutane or 2-mercaptoethanol, preferably in anassay system using the ATP/ADP conversion. Thedifference in the two values found is due to theCPK-MB present. The invention is of particularutility in the diagnosis and treatment ofmyocardial damage.