14-Hydroxy-4,20,22-bufatrienolide 3-pyranosides - for treating cardiac insufficiency giving good blood levels with low risk of accumulation

摘要

Novel pyranoside of formula (I): (where P is of formula (II) R1-3 are H or acyl, esp. acetyl, benzoyl or p-nitrobenzoyl) are used for treatment of cardiac insufficiency. Unlike proscillaridin, (I) are completely absorbed and eliminated at an optimal speed so that good blood levels may be obtd. without fear of accumulation.