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Methyl-isoxazole-carboxylate salts of theophylline derivs. - with antilipolytic and hypolipaemic activity
Methyl-isoxazole-carboxylate salts of theophylline derivs. - with antilipolytic and hypolipaemic activity
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机译:茶碱的甲基-异恶唑-羧酸盐衍生。 -具有抗脂解和降血脂活性
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摘要
New 5-methylisoxazole-3-carboxylate salts of formula (I): (where R1 and R2 are H, 1-6C alkyl, hydroxyalkyl or alkoxyalkyl or cyclohexyl). (I) have antilipolytic and hypolipaemic activity. The prefd. cpd. is (I; R1=Me, R2 = CH2CH2OH). In an example, this is prepd. by reacting 7- 3-(N-methyl-N-hydroxyethylamino)-2-hydroxyethylamino)-2-hydrox- ypropyl -theophylline with 5-methylisoxazole-3-carboxylic acid.
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