首页> 外国专利> Anti inflammatory and vasculotropic compsns. - contg. a synergistic combination of proteolytic enzyme, Ruscus Aculeatus extract and vitamin P

Anti inflammatory and vasculotropic compsns. - contg. a synergistic combination of proteolytic enzyme, Ruscus Aculeatus extract and vitamin P

机译:抗炎和促血管复合物。 -续蛋白水解酶,红景天提取物和维生素P的协同组合

摘要

Compositions containing an anti-inflammatory proteolytic enzymatic complex (I), and a vasculotropic mixture (II) of a Ruscus Aculeatus L extract and =1 Vitamin P factor, are new. The enzymatic complex (I) is pref. isolated from the pancreas and has chymotripsic anc trypsic activity, esp. 15000U of chymotrypsin and 10500U of trypsin (NF units). The extracts used in (II) are pref. sterolic heterosides prepd. from rhizomes of R. Aculeatus. The vitamin P factor used in (II) may be a chalconised and alkylated water soluble derivative of flavonic glucosides, esp. hesperidin-methyl-chalcone. Pref. presentation of the compsn is a tablet with (I) in the core and enteric coated and (II) in an outer layer. Used as anti-inflammatories and vaculotropes in human and veterinary medicine, esp. for haemorrhoidal crises, post-traumatic vascular disorders or oedema, in gynaecology for pelvic congestion and pain, and various disorders associated with oral and/or intra/uterine contraception. Synergism exists between (I) and (II).
机译:含有抗炎蛋白水解酶复合物(I)和红刺L提取物和> = 1维生素P因子的促血管混合物(II)的组合物是新的。酶复合物(I)是优选的。从胰脏中分离出来,具有胰糜蛋白酶和胰蛋白酶的活性,特别是。 15000U的胰凝乳蛋白酶和10500U的胰蛋白酶(NF单位)。 (II)中使用的提取物是优选的。制备甾体杂化物。来自R. Aculeatus的根茎。 (II)中使用的维生素P因子可以是黄酮葡萄糖苷的特别是烷基化和烷基化的水溶性衍生物。橙皮苷-甲基查尔酮。首选compsn的展示形式是片剂,其中(I)处于芯层,肠溶包衣,(II)位于外层。尤其是在人类和兽医学中用作抗炎药和真空制剂。用于痔疮危机,创伤后血管疾病或水肿,妇科骨盆充血和疼痛以及与口服和/或子宫内/子宫避孕有关的各种疾病。 (I)和(II)之间存在协同作用。

著录项

  • 公开/公告号FR2377201B1

    专利类型

  • 公开/公告日1979-04-20

    原文格式PDF

  • 申请/专利权人 FABRE PIERRE SA;

    申请/专利号FR19770001290

  • 发明设计人

    申请日1977-01-18

  • 分类号A61K37/48;A61K31/70;A61K35/78;

  • 国家 FR

  • 入库时间 2022-08-22 19:36:02

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