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Film drug a base of an active substance is action against angina, such as the nitroglycerine or isosorbide dimitrate

机译:薄膜药物中一种活性物质的基础是抗心绞痛,例如硝酸甘油或二山梨酸异山梨酯

摘要

P the invention relates to the medicine. / p & & p & the antianginal film forming the subject of the invention is characterized in particular in that it is present in the form of a plate or blade of 0,1 to 1,5 mm thickness composed of a cosmetic excipient, which is soluble and resorbable constituted by a homopolymer of acrylic or vinyl acetate, or a copolymer of those - thereof with an acrylate, this copolymer comprising 99 to 70% by weight of acrylic and vinyl acetate for 1 to 30% by weight of acrylate with a molecular weight of 50 000 to 1 000 000, and an active substance in action antianginal. Fig. 1 shows, in particular, by way of comparison, the variation delta if% as a function of time of the index systolic responses at% with respect to the initial value, in the case of the film according to the invention and in that of a medicine. / p & & p & the films in question have a prolonged duration of action, allow a high precision of metering of the active substance and are endowed with good stability on storage. / p
机译:

本发明涉及药物。 & &形成本发明主题的抗心绞痛膜的特征特别在于,它以厚度为0.1至1.5mm的板或刀片的形式存在,该板或刀片由化妆品赋形剂组成,该化妆品赋形剂是可溶的和可吸收的,由化妆品赋形剂构成。丙烯酸或乙酸乙烯酯的均聚物,或它们与丙烯酸酯的共聚物,该共聚物包含99至70%重量的丙烯酸和乙酸乙烯酯,相对于1至30%的丙烯酸酯,分子量为50,000至1 000 000,以及抗心绞痛的活性物质。图1特别地通过比较示出了在根据本发明的膜的情况下,相对于初始值,作为指数的收缩收缩反应的时间的函数Δt%相对于初始值的变化Δif%。一种药物。 & &所讨论的薄膜具有延长的作用时间,允许高精度计量活性物质,并具有良好的储存稳定性。

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