首页> 外国专利> TESTING MEANS AND IMPLEMENT FOR MEASURING OXIDIZABLE SUBSTANCE* METHOD OF MAKING SAID MEANS AND IMPLEMENT* AND MEASURING METHOD AND TESTING SYSTEM FOR OXIDIZABLE SUBSTANCE

TESTING MEANS AND IMPLEMENT FOR MEASURING OXIDIZABLE SUBSTANCE* METHOD OF MAKING SAID MEANS AND IMPLEMENT* AND MEASURING METHOD AND TESTING SYSTEM FOR OXIDIZABLE SUBSTANCE

机译:氧化性物质的测定方法和实施方法*氧化性物质的测定方法和实施方法以及测定方法和测试系统

摘要

Test means, such as a composition or device, method of making a test device and process for determination of at least one oxidizing substance, such as a peroxide, are disclosed. More particularly, the contemplated test means comprises a hydrazone and 8-amino-1-napthol-5,7-disulfonic acid (Chicago acid). Further provided is a test system for the determination of a constituent in a sample, having means responsive to the presence of said constituent in said sample to produce at least one oxidizing substance and a composition for determining said at least one oxidizing substance, wherein said composition comprises a hydrazone and 8-amino-1-napthol-5,7-disulfonic acid (Chicago acid). The test system is preferably of the type which determines peroxides formed from enzymatic conversion of constituents in biological fluids. When in the form of compositions the test means can optionally be incorporated with a carrier, such as a tablet or matrix, to provide a test device. The test system is highly sensitive to low levels of body fluid constituents to be detected, while also being highly resistant to interfering reducing substances, such as ascorbic acid, often present in body fluids.
机译:公开了诸如组合物或装置的测试装置,制造该装置的方法以及用于确定至少一种氧化性物质如过氧化物的方法。更具体地,预期的测试手段包括a和8-氨基-1-萘-5,7-二磺酸(芝加哥酸)。还提供了一种用于确定样品中成分的测试系统,其具有响应于所述样品中所述成分的存在以产生至少一种氧化物质的装置和用于确定所述至少一种氧化物质的组合物,其中所述组合物包含a和8-氨基-1-萘-5,7-二磺酸(芝加哥酸)。测试系统优选地是确定由生物流体中的成分的酶促转化形成的过氧化物的类型。当为组合物形式时,测试工具可任选地与诸如片剂或基质的载体结合以提供测试装置。该测试系统对要检测的少量体液成分高度敏感,同时还对体液中经常存在的干扰性还原物质(例如抗坏血酸)具有高度的抵抗力。

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