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foerfarande foer framstaellning av i stabil emulsion av i syre transporterande perfluorkolvaete

机译:仍用于制备稳定的氧气传输全氟化碳乳液

摘要

The stable emulsion contains the following components: (A) At least one perfluorocarbon compound which contains 9 to 11 carbon atoms, selected from the series comprising perfluorodecalin, perfluoromethyldecalin, perfluoroalkylcyclohexane having 3 to 5 carbon atoms in the alkyl, perfluoroalkyltetrahydrofuran having 5 to 7 carbon atoms in the alkyl, perfluoroalkyltetrahydropyran having 4 to 6 carbon atoms in the alkyl and perfluoroalkanes having 9 to 11 carbon atoms; (B) At least one perfluoro-tertiary-amine having 9 to 11 carbon atoms, selected from the series comprising perfluoro-tertiaryalkylamines having 9 to 11 carbon atoms, perfluoro-N-alkylpiperidines having 4 to 6 carbon atoms in the alkyl and perfluoro-N-alkylmorpholines having 5 to 7 carbon atoms in the alkyl; a high-molecular-weight, non-ionic surfactant having a molecular weight of 2,000 to 20,000; a phospholipoid; at least one fatty acid having 8 to 22 carbon atoms or its physiologically acceptable salt or monoglyceride; the ratio by weight of the perfluorocarbon compound (A) to the perfluoro-tertiary-amine (B) being 95-50:5-50. Such an emulsion is stable even upon prolonged storage.
机译:该稳定的乳液包含以下组分:(A)至少一种含有9-11个碳原子的全氟化碳化合物,其选自烷基中的全氟萘烷,全氟甲基十氢化萘,具有3至5个碳原子的全氟烷基环己烷,具有5至7个碳的全氟烷基四氢呋喃在烷基中的原子,在烷基中具有4至6个碳原子的全氟烷基四氢吡喃和具有9至11个碳原子的全氟烷烃; (B)至少一种具有9至11个碳原子的全氟叔胺,选自包括具有9至11个碳原子的全氟叔烷基胺,在烷基中具有4至6个碳原子的全氟-N-烷基哌啶和全氟-在烷基中具有5至7个碳原子的N-烷基吗啉;高分子量的非离子表面活性剂,分子量为2,000至20,000;磷脂;至少一种具有8至22个碳原子的脂肪酸或其生理上可接受的盐或甘油单酸酯;全氟化碳化合物(A)与全氟叔胺(B)的重量比为95-50∶5-50。这样的乳液即使在长期保存下也是稳定的。

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