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METHOD FOR THE PREPARATION OF 2-DEOXYFORTIONICIN A,4-N-ALKYL AND 4-N-ACYL-2-DEOXYFORTIONICIN B DERIVATIVES AND INTERMEDIATES THEREFOR
METHOD FOR THE PREPARATION OF 2-DEOXYFORTIONICIN A,4-N-ALKYL AND 4-N-ACYL-2-DEOXYFORTIONICIN B DERIVATIVES AND INTERMEDIATES THEREFOR
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机译:制备2-去氧甲壳素A,4-N-烷基和4-N-酰基-2-去氧甲壳素B衍生物并介导中间体的方法
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摘要
2-Deoxyfortimicin, A, 2-deoxy-4-N-alkyl fortimicins and 2-deoxy-4-N-acyl fortimicins represented by the formula IMAGE wherein R is selected from the group consisting of acyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl, an amino acid residue, hydroxyacyl, loweralkyl, aminoloweralkyl, N-monoloweralkylaminoloweralkyl, hydroxyloweralkyl, N-N-diloweralkylaminoloweralkyl or hydroxy-substituted aminoloweralkyl, and the pharmaceutically acceptable salts thereof; intermediates therefor; and pharmaceutical compositions containing the compounds of this invention.
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