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PEPTIDES HAVING STRONG LH-RH/FSH-RH ACTIVITY AND PROCESS FOR THEIR MANUFACTURE

机译:具有强LH-RH / FSH-RH活性的肽及其制造工艺

摘要

PEPTIDES HAVING STRONG LH-RH/FSH-RH ACTIVITY AND PROCESS FOR THEIRMANUFACTUREAbstract of the disclosure:The present invention relates to peptides having strong LH-RH/FSH-RH activity, wherein Gly in 6-position is replaced bydifferent substituted amino acids and in 10-position there isGlycinamide or glycin in 10-position is replaced by a NH-alkylgroup with 1 - 3 carbon atoms or a NH-cyclopropyl group. Theinvention relates as well to a process for manufacturing saidpeptides, and to pharmaceutical preparations containing saidpeptides.
机译:LH-RH / FSH-RH活性强的肽及其制备方法制造公开摘要:本发明涉及具有强LH-RH /的肽FSH-RH活性,其中6位的Gly被不同的取代氨基酸,在10位上10位的甘氨酰胺或甘氨酸被NH-烷基取代具有1-3个碳原子的基团或NH-环丙基。的本发明还涉及制造所述的方法肽,以及含有上述成分的药物制剂肽。

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