AbstractNew 3,11-dihydro-6H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]-pyrido[4,3-d]pyrimidin-6-one and new derivatives thereof, use-ful as antiinflammatory agents, have the general formulawherein R1 and R3 each is hydrogen, lower alkyl, phenyl orphenyl-lower alkylene; R2, R4 and R6 each is hydrogen or loweralkyl; R5 is hydrogen, lower alkyl, phenyl-lower alkylene, ben-zoyl, substituted benzoyl wherein the phenyl substituent ishalogen, lower alkyl or lower alkoxy, lower alkanoyl, loweralkoxy-lower alkylene, lower alkylthio-lower alkylene, amino-lower alkylene or alkylene wherein R7 and R8 eachis lower alkyl or join in forming piperidine, morpholine, thia-morpholine or piperazine; and acid addition salts thereof.
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机译：抽象新型3,11-二氢-6H-吡唑并[1,5-a]吡唑并[4'，3'：5,6]-吡啶并[4,3-d]嘧啶-6-及其新衍生物，用于作为抗炎药，具有以下通式其中R1和R3各自为氢，低级烷基，苯基或苯基-低级亚烷基; R 2，R 4和R 6均为氢或更低烷基; R5是氢，低级烷基，苯基-低级亚烷基，本-唑基，取代的苯甲酰基，其中苯基取代基是卤素，低级烷基或低级烷氧基，低级烷酰基，低级烷氧基-低级亚烷基，低级烷硫基-低级亚烷基，氨基-低级亚烷基或亚烷基，其中R 7和R 8各自是低级烷基或连接形成哌啶，吗啉，硫杂-吗啉或哌嗪;及其酸加成盐。
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