Latex coated with a polyhydroxy compound, process for the preparation of this latex, immunological reagent containing this latex, process for the preparation of this reagent, application of this reagent, testing procedure utilising this reagent and reagent kit containing this reagent

摘要

A water-insoluble immunological reagent having a specific gravity of about that of water comprising discrete particles of a latex carrier to which a water-soluble polyhydroxy compound is covalently bound having condensed thereto through a covalent link a known immunologically active material (including enzymes, proteins, hormones, antigens, antibodies, polysaccharides, fungi, bacteria, protozoa, viruses and rickettsia); a process for the manufacture of said reagent; an immunological method using said reagent; a kit containing said reagent and the use of said reagent in immunological determinations. A latex comprises discrete particles of a latex carrier to which a polyhydroxy compound is covalently bonded.