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Beta-lactones derived from 2-hydroxycyclopentane carboxylic acid, process for their preparation, pharmaceutical compositions containing them; 2-hydroxycyclopentane carboxylic acid derivatives and related beta-lactones
Beta-lactones derived from 2-hydroxycyclopentane carboxylic acid, process for their preparation, pharmaceutical compositions containing them; 2-hydroxycyclopentane carboxylic acid derivatives and related beta-lactones
Novel beta -lactones of 2-hydroxy-cyclopentane-carboxylic acids of the formula IMAGE I wherein R1 is selected from the group consisting of hydrogen and methyl and R2 is selected from the group consisting of -CH2-O-CH2-CH3 and -X-Ar, X is selected from the group consisting of -O- and -CH2-, Ar is an optionally substituted member selected from the group consisting of thienyl, thiazolyl, phenyl and thiadiazolyl, the optional substituents being at least one member selected from the group consisting of halogen and -CF3 and thw wavy lines indicate that the groups may be in the alpha , beta or beta , alpha -positions or mixtures thereof having hypotensive activity and their preparation.
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