Steroidal phosphonothioate compounds, process for preparing them, compositions containing said compounds, process for preparing said compositions, method of producing an antiserum and method of radioimmunoassay

摘要

Novel phosphonothioate compounds of the general formulawherein R₁ is lower alkylR₂ is a steroid residue which is linked to the rest of the molecule through any carbon atom which is not one of the carbon atoms forming a ring junction, orthrough a side chain carbon atom, andn is 1 to 4, are disclosed as well as the use of these compounds as immunogenic haptens.;Immunogenic hapten-protein complexes and conjugates of these phosphonothioate compounds and of steroid phosphates are also disclosed.