FOERFARANDE Før 11A-11A DEHALOGENERING AV-HALO-6-METYLENTETRACYKLINER

摘要

1459861 6 - Demethyl - 6 - deoxy - 6 - methyllenetetracyclines PFIZER Inc 2 Jan 1974 [21 June 1973] 00106/74 Heading C2C 6 - Demethyl - 6 - deoxy - 6 - methylenetetracyclines are prepared by contacting an 11ahalo - 6 - demethyl - 6 - deoxy - 6 - methylenetetracycline with at least an equimolar amount of a secondary or tertiary phosphine or a tertiary phosphite in a reaction-inert solvent to effect 11a-dehalogenation.