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quinolone compounds and pharmaceutical compositions containing antiipertensi you delay process for producing them
quinolone compounds and pharmaceutical compositions containing antiipertensi you delay process for producing them
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机译:喹诺酮类化合物和含有抗高血压药的药物组合物会延缓生产过程
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摘要
Novel quinolones of the general formula IMAGE wherein n is 0, 1 or 2; R1 is C1-4 alkyl; and R3 is hydrogen, C1-4 alkyl, methoxy, methylthio, halo or trifluoromethyl. These compounds have antihypertensive activity and may be used for treating hypertension in mammals. The quinolones are administered in novel therapeutic compositions comprising a quinolone of the above general formula together with a pharmaceutically acceptable carrier. Processes for making the novel quinolones are described.
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机译:通式的新型喹诺酮,其中n为0、1或2; R1为C1-4烷基; R 3是氢,C 1-4烷基,甲氧基,甲硫基,卤素或三氟甲基。这些化合物具有抗高血压活性,可用于治疗哺乳动物的高血压。喹诺酮以新型治疗组合物的形式给药,所述治疗组合物包含上述通式的喹诺酮和药学上可接受的载体。描述了制备新型喹诺酮的方法。
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