首页> 外国专利> sulfonsaeurealkalimetallsalz - and sulfone amide derivatives of 6,6 '- methylene - to - (2,2,4 - trimethylsulphonium - 1,2 - dihydropyridines of quinoline) and its dimers and trimers condensation products, a process for the preparation thereof and pharmaceutical compositions containing same

sulfonsaeurealkalimetallsalz - and sulfone amide derivatives of 6,6 '- methylene - to - (2,2,4 - trimethylsulphonium - 1,2 - dihydropyridines of quinoline) and its dimers and trimers condensation products, a process for the preparation thereof and pharmaceutical compositions containing same

机译:6,6'-亚甲基-对-(2,2,4-三甲基s-1,2-二氢吡啶并喹啉)的磺酰脲基碱金属盐及其磺酰胺衍生物,其二聚体和三聚体缩合产物,其制备方法和药物组合物包含相同

摘要

The invention relates to water-soluble alkali salts of mono- and disulfonic acid derivatives and mono- and disulfonamide derivatives of 6,6'-methylene-bis-(2,2,4-trimethyl-1,2-dihydroquinoline) and dimer and/or trimer condensation products thereof bound with a methylene bridge at the 8 or 8' position. The new compounds are radioprotective and radiosensibilizers at the same time, and may be used both in the therapy and prophylaxis of malignant tumors.
机译:本发明涉及6,6′-亚甲基-双-(2,2,4-三甲基-1,2-二氢喹啉)和二聚体的单磺酸和二磺酸衍生物和单磺酸酯和二磺酰胺衍生物的水溶性碱金属盐。 /或其三聚体缩合产物在8或8'位置与亚甲基桥键合。新化合物同时具有放射防护作用和放射增敏作用,可用于恶性肿瘤的治疗和预防。

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