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Antihypertensive 2-indolyl:piperidinyl-1-benzo-dioxanyl ethanol cpds. - which are prepd. from indolyl:piperidine cpd. and oxiranyl benzodioxan
Antihypertensive 2-indolyl:piperidinyl-1-benzo-dioxanyl ethanol cpds. - which are prepd. from indolyl:piperidine cpd. and oxiranyl benzodioxan
2-Indolyl-piperidinyl-1-benzodioxanyl methanol derivs. of formula (I) in racemic or optically active forms and their salts are new: (where R1 = H, 1-5C alkoxy, Cl, Br or F, R1 = H, 1-5C alkyl, R2 = 1-5C alkyl, Y and Z = H or together form a double bond, R2 may also be H when Y and Z form a double bond or when Y and Z = H, and R1 = Cl, Br or F). Cpds. (I) are antihypertensives. Also claimed are the 3 cpds. (I, R1 = 5-methoxy, R2=Y=Z=H, R1 = H), (I, R1 = 66-methoxy, R2 =Y=Z=H, R1=CH3) and (1:R1=H, R2=Y=Z=H, R1=CH3) and their salts and isomers.
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机译：2-吲哚基-哌啶基-1-苯并二恶烷基甲醇衍生。外消旋或旋光形式的式（I）的式（I）及其盐是新的：（其中R 1 = H，1-5 C烷氧基，Cl，Br或F，R 1 = H，1-5 C烷基，R 2 = 1-5 C烷基， Y和Z = H或一起形成双键，当Y和Z形成双键或当Y和Z = H，且R1 = Cl，Br或F时，R2也可以是H。 Cpds。 （一）是降压药。还要求保护的是3个cpds。 （I，R1 = 5-甲氧基，R2 = Y = Z = H，R1 = H），（I，R1 = 66-甲氧基，R2 = Y = Z = H，R1 = CH3）和（1：R1 = H ，R2 = Y = Z = H，R1 = CH3）及其盐和异构体。
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