Carboxy:methylcellulose matrix for slow release of volatile cpd. - contains tri:ethanolamine, stearin and an alcohol e.g. cetyl is esp. useful for perfumes, insect repellents eczema treatment etc.

摘要

Process for the production of a matrix, having at least one active constituent which will be released progressively, by a) absorption of 0.5-5 wt % of carboxymethylcellulose in 70 wt % of water, b) emulsification of the hydrated carboxymethylcellulose with 1% of triethanolamine, c) addition of 5 wt % of stearin and d) addition and homogenisation of a solution of the active constituent in a solvent compatible with carboxymethylcellulose e.g. a 1-10C carboxylic alcohol, such as cetyl alcohol. Progressive release compositions for topical application in the form of creams useful as cosmetics (perfumes, moisturising creams etc.) and pharmaceuticals (eczema treatment trinitroglycerin etc.). The compositions are esp. useful in the sustained release.