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Composition adapted for the determination of tri-iodo thyronine and diagnosis method employing same
Composition adapted for the determination of tri-iodo thyronine and diagnosis method employing same
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机译:适用于三碘甲状腺素测定的组合物及其诊断方法
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摘要
A composition for diagnostic use is disclosed, more particularly for the dosage of tri-iodo thyronine in human blood serum: the subject composition comprises tri-iode thyronine as such and an enzyme which is covalently bonded to tri-iodo thyronine. A diagnostic method is also disclosed, which is intended for using the above specified composition in diagnostic runs. The method, briefly resumed, consists removing the tri- iodo thyronine of the serum sample being assayed by means of an insolubilized anti-T.sub.3 antibody and treating the residue with the sensibilized enzyme which is nothing else than the covalent formed by tri- iodo thyronine and an appropriate enzyme, such as carbonic anhydrase.
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