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PRODUCTION OF NNGLYCOSYL DERIVATIVE OF POLYENEMACRORIDE
PRODUCTION OF NNGLYCOSYL DERIVATIVE OF POLYENEMACRORIDE
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机译:聚甲基丙烯酸缩水甘油酯衍生物的生产
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摘要
The amino group-containing polyene macrolide is reacted with a mono- or oligosaccharide of the aldose or ketose series in an organic solvent or an organic solvent mixture. In order to be able to use an inexpensive, non-flammable solvent, the N-glycosyl derivative produced is precipitated from the reaction medium by means of water or an aqueous solution of an inorganic salt, purified by crystallisation from a higher alcohol, and optionally converted into a salt.
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