PROCEDURE FOR THE PREPARATION OF 2-4-(2-FUROYL)-PIPERAZINE-1-YL YL-4-AMINO-6,7-DIMETHOXYCHINAZOLINE.HYDROCHLORIDE WITH BLOOD CONTROL AND A MEDICINAL PRODUCT WITH BLOOD CONTROL THAT IS APPROVED.

摘要

The invention relates to novel and valuable crystalline forms of the hypotensive agent prazosin hydrochloride. The anhydrous alpha -form is preferred because it is relatively non-hygroscopic and hence possesses important advantages in handling and formulation. The polyhydrate form of prazosin hydrochloride is preferred because of its low, uniform rate of dissolution.