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A process for preparing a pharmaceutical composition for topical application, used in the treatment of acne.
A process for preparing a pharmaceutical composition for topical application, used in the treatment of acne.
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机译:一种用于治疗痤疮的局部用药物组合物的制备方法。
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摘要
Topical compositions, containing tetracycline, tetracycline salts or tetracycline derivatives, which do not cause skin yellowing, are disclosed. These compositions are formulated such that, upon application to the skin, the tetracycline component recrystallizes in small, irregular crystals at the skin surface. Preferred compositions are buffered at a pH between about 2.0 and 4, such as by the addition of citric acid. The method of treating skin disorders such as acne, using these compositions is also disclosed.
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