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A process for preparing 3 - (4 - piridinil) - 2 - ciclohe Xen - 1 - ona oxime

机译:一种制备3-(4-吡咯烷酮)2-2-环戊烯Xen-1-ona肟的方法

摘要

Production method of 3 - (4 - piridinil) - 2 - ciclohexen - 1 - ona oxime. Heat The 5-oxo - 2 - (4 - piridinil) - carbonyl Ethyl hexanoate - with an excess of aqueous sulfuric acid. Neutralizes the excess acid. The resulting product was extracted with Isopropyl alcohol. The aqueous Layer was removed and hydroxylamine hydrochloride dense is added to the solution.The mixture was Stirred at reflux, drying and basifica and Evaporated until the final product is isolated. It is used as an intermediate in the preparation of Antibacterial agents.
机译:3-(4-吡咯烷酮)-2-环己酮-1-肟的生产方法。加热5-氧代-2-(4-吡啶啉)-羰基己酸乙酯-与过量的硫酸水溶液一起加热。中和过量的酸。所得产物用异丙醇萃取。除去水层,并向溶液中加入浓盐酸羟胺。将混合物回流搅拌,干燥并碱化,蒸发直至分离出最终产物。它用作制备抗菌剂的中间体。

著录项

  • 公开/公告号ES8107187A1

    专利类型

  • 公开/公告日1981-12-16

    原文格式PDF

  • 申请/专利权人 STERLING DRUG INC.;

    申请/专利号ES19800495967

  • 发明设计人

    申请日1980-10-16

  • 分类号C07D213/74;A61K31/44;

  • 国家 ES

  • 入库时间 2022-08-22 13:21:07

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