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Method for preparing a stable Composition of s-adenosyl-l-methionine

机译:一种稳定的s-腺苷-1-蛋氨酸组合物的制备方法

摘要

Method for Preparation of a stable Composition of asdenosil S - - L - methionine (SAM). They are grown in a medium containing methionine, saccharonyces microorganisms of the genus Candida, or others. Separate cultivation of microorganism cells and subjected to extraction with an Acid or a alcohilo formate. The extract containing Sam is Purified by Conventional Methods.Preparing an aqueous solution with a Salt of Sam containing 0.5 - 3 mol / mol of acid and Sam with a Bivalent or Trivalent metal salt is Soluble in water. Remove the aqueous Solvent or an organic Solvent is added, and let it precipitate. Application in Pharmaceutical preparations for the treatment of fatty liver, hyperlipemia, arteiosclerosis and Other Ailments.
机译:制备稳定的腺苷S--L-蛋氨酸(SAM)组合物的方法。它们在含有蛋氨酸,念珠菌属的酵母菌等的培养基中生长。分开培养微生物细胞,并用酸或甲酸铝乙酯萃取。用常规方法纯化含有山姆的提取物。用含0.5-3mol / mol酸的山姆盐和含二价或三价金属盐的山姆制备水溶液可溶于水。除去水性溶剂或添加有机溶剂,然后使其沉淀。在治疗脂肪肝,高脂血症,动脉硬化和其他疾病的药物制剂中的应用。

著录项

  • 公开/公告号ES8200657A1

    专利类型

  • 公开/公告日1982-02-01

    原文格式PDF

  • 申请/专利权人 KANEGAFUCHI CHEMICAL INDUSTRY COMPANYLIMITED;

    申请/专利号ES19800497403

  • 发明设计人

    申请日1980-12-03

  • 分类号C07C149/247;A61K31/095;

  • 国家 ES

  • 入库时间 2022-08-22 13:20:58

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