New procedure for the preparation of (-) - (4a-12b-trans), 2,3,4,4a, 7,8,12b, 13-octahidro-1H-tieno (3,4,5-fg) benzo ( 1,2) ciclohepta (4,3-b) quinolizin (Machine-translation by Google Translate, not legally binding)

摘要

Procedure for preparation of (-) - (4a-12b-trans), 2,3,4,4a, 7,8,12b, 13-octahydro-1H-thienum (3,4,5-fg) benzo (1, 2) ciclohepta (4,3b quinolyzine of formula (I) is reduced to an amid of formula (II) with a mixture of lithium and aluminum hydride and aluminum trichloride in equimolecular proportion, in ethyl etheric anhydro and reflux temperature. The obtained compound is treated at a temperature of 70-100 c. With mercury acetate, in a weak acid environment, as acetic acid diluted to 5 per 100 in water, precipitated with percororic acid at 60 per 100. (Machine-translation by Google Translate, not legally binding)