首页>
外国专利>
Hydrogenation products of mevinolin and dihydromevinolin, a process for preparing the same and an antihypercholesterolemic pharmaceutical composition containing the same.
Hydrogenation products of mevinolin and dihydromevinolin, a process for preparing the same and an antihypercholesterolemic pharmaceutical composition containing the same.
展开▼
机译:美维诺林和二氢美维诺林的加氢产物,其制备方法和包含其的抗高胆固醇血症药物组合物。
展开▼
页面导航
摘要
著录项
相似文献
摘要
Hydrogenation of the natural fermentation product, mevinolin, MK-803, results in the production of dihydro- and tetra-hydro derivatives and hydrogenation of the naturally occurring dihydromevinolin results in the formation of a tetrahydro derivative. These several products with the exception of cis-(4 alpha beta , 8 alpha beta -) -tetrahydromevinolin are potent inhibitors of cholesterol biosynthesis.
展开▼