A process for the preparation of Derivatives of - toina Hidan.

摘要

Method for obtaining Derivatives of Hydantoin and its Salts, wherein R1 is c1-4 alkyl; R2 is Hydrogen or c1-4 alkyl hydroxyl hydroxyl; R3 or R5 is protected, or is hirogeno 1-6 alkyl; R4 can be several types of Radicals; and - CH2 - H2, - ch = CH - or - C = C, and N is 1 to 5.Consists in the reduction reaction of a compound in which R1, R2, R3, R4, R5, and "n" and have the same meaning with reducing Agent of the carbonyl Group, following methods convencionaes. These compounds have applications for its pharmacological activity antisecrecion gastric antiulcer, on smooth muscle and vascular activity.