QUATERNARY AMMONIUM SALTS OF DANTROLENE AND CLODANOLENE

摘要

ABSTRACT OF THE DISCLOSURECertain quaternary ammonium salts of dantrolene andclodanolene of the formula:wherein X is 4-nitro or 3,4-dichloro; .theta.NR4 is N-methylpyridinium,3,7-diamino-2,8-dimethyl-5-phenylphenazinium, 2,3-dimethyl-1-phenyl-4-trimethylammonium -3-pyrazoline-5-one, 1,3-dimethylimi-dazolium, choline, or 2-methyl-2-trimethylammonium-1-propanol;and n is 0, 0.75 or 1.5, are effective skeletal muscle relaxants.